MYCT1

mass-spec protein & survival
Survivalmass-specKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, MYCT1 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated MYCT1 data layer compared with 23 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher MYCT1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated MYCT1 expression acts as an unfavorable survival marker, although some lineages such as CCRCC show a favorable association.

CCRCC, LUAD, and GBM are the cancer types where MYCT1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
CCRCCDFSQuartileAll1.0000.443<.00148view →
LUADDFSTertileIII,IV0.3830.967.00125view →
GBMOSQuartileAll0.3020.755.0034view →
LSCCDFSTertileAll0.8970.971.0124view →
Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

MYCT1–CCRCC (DFS)

Kaplan–Meier survival curve for MYCT1 mass-spec protein-high vs -low samples in CCRCC.

Open the CCRCC breakdown →

Exploration