MYCT1

Across TCGA cell cohorts, MYCT1 mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible MYCT1-associated genes across cancer lineages are MS4A4A, ZNF831, and CDX4. Each is linked with MYCT1 in more than 1 cancer types. Because this analysis shows association rather than direction, both MYCT1-to-partner and partner-to-MYCT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MS4A4A grouped by MYCT1-low versus MYCT1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MYCT1→partner) and Y-score (partner→MYCT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	MS4A4A →	+0.157	+3.000	<.001	.006	3	1
LARGE_INTESTINE	ZNF831 →	+0.011	+3.103	<.001	.004	3	1
LARGE_INTESTINE	CDX4 →	+0.011	+3.217	<.001	.006	3	1
LARGE_INTESTINE	TAFA1 →	+0.234	+3.103	.002	.004	3	1
LARGE_INTESTINE	SMIM33 →	+0.728	+3.426	<.001	.007	3	1
LUNG_SCLC	PRDM14 →	+0.314	+4.209	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

MS4A4A by MYCT1 expression — LARGE_INTESTINE

Explore this box plot interactively →