MYCL

Across TCGA patient cohorts, MYCL protein abundance is significantly associated with the RNA expression of many other genes, with 3,980 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MYCL-associated genes across cancer lineages are BET1, NMRK1, and PNPO. Each is linked with MYCL in more than 1 cancer types. Because this analysis shows association rather than direction, both MYCL-to-partner and partner-to-MYCL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MYCL versus BET1 in OV, with a Pearson correlation of -0.80.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MYCL→partner) and Y-score (partner→MYCL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	BET1 →	-0.681	-1.027	<.001	<.001	3	1
OV	NMRK1 →	-0.878	-1.128	.007	<.001	3	1
OV	PNPO →	-0.961	-0.918	<.001	<.001	3	1
OV	PMS2 →	-0.751	-0.855	<.001	.001	3	1
OV	TUBA4A →	-2.420	-0.997	.001	.005	3	1
OV	TBC1D5 →	-0.551	-0.918	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,980 associations by consensus.

MYCL vs BET1 — OV

Explore this scatter interactively →