MYCL

Across TCGA cell cohorts, MYCL RNA expression is significantly associated with the go_rna of many other GO terms, with 4,450 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible MYCL-associated GO terms across cancer lineages are Coenzyme A metabolic process, Dentinogenesis, and Copper ion export. Each is linked with MYCL in more than 10 cancer types. Because this analysis shows association rather than direction, both MYCL-to-partner and partner-to-MYCL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Coenzyme A metabolic process grouped by MYCL-low versus MYCL-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MYCL→partner) and Y-score (partner→MYCL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Coenzyme A metabolic process →	+0.097	+1.136	.001	.005	3	11
OVARY	Dentinogenesis →	-1.336	-1.132	<.001	<.001	3	10
BREAST	Copper ion export →	-0.159	-1.124	<.001	<.001	3	10
OVARY	Regulation of smooth muscle cell-matrix adhesion →	-0.678	-1.080	<.001	<.001	3	10
LIVER	Urokinase plasminogen activator signaling pathway →	-1.455	-1.161	.001	<.001	3	10
LUNG_NSCLC_LUSC	Regulation of isotype switching to IgE isotypes →	-1.174	-1.288	<.001	.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,450 associations by consensus.

Coenzyme A metabolic process by MYCL expression — LIVER

Explore this box plot interactively →