MYCBP2-AS1

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, MYCBP2-AS1 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated MYCBP2-AS1 data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher MYCBP2-AS1 RNA is associated with better overall survival. In most high-consensus cancer types, elevated MYCBP2-AS1 expression acts as an unfavorable survival marker, although some lineages such as HNSC and PAAD show a favorable association.

HNSC, BLCA, and UVM are the cancer types where MYCBP2-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
HNSCOSTertileIV0.5910.388.00360view →
BLCADFSTertileAll0.5430.675.00446view →
UVMDFSMedianIII,IV0.1830.824.00126view →
PAADDFSQuartileAll0.6310.345.00425view →
LAMLDFSMedianAll0.4750.278.00420view →
UCSDFSMedianIII,IV0.5770.265.00518view →
LIHCDFSQuartileIII,IV0.6390.331.01013view →
BRCAOSQuartileIV0.5230.890.0146view →
MESOOSQuartileAll0.7200.232.0266view →
READOSTertileIII,IV0.8450.564.0196view →
ESCAOSMedianIII,IV0.5820.326.0285view →
KIRPDFSMedianAll0.4460.749.0025view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

MYCBP2-AS1–HNSC (OS)

Kaplan–Meier survival curve for MYCBP2-AS1 RNA-high vs -low samples in HNSC.

Open the HNSC breakdown →

Exploration