MYBPHL

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, MYBPHL mutation is significantly associated with the total protein of many other genes, with 5 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MYBPHL-associated genes across cancer lineages are Rictor_pT1135, Caspase-7-cleavedD198, and INPP4B. Each is linked with MYBPHL in more than 1 cancer types. Because this analysis shows association rather than direction, both MYBPHL-to-partner and partner-to-MYBPHL results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MYBPHL→partner) and Y-score (partner→MYBPHL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECRictor_pT1135 →-0.141-3.000.017.03731
UCECCaspase-7-cleavedD198 →+1.150+2.827<.001.03531
UCECINPP4B →-0.524-2.986.005.03711
UCECp62 Lck ligand →+0.516+3.000.006.03711
UCECCyclin-B1 →+0.714+3.000.028.03711
Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Exploration