Across TCGA cell cohorts, MYBPHL mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible MYBPHL-associated genes across cancer lineages are GSG1L2, RGSL1, and SPAG11A. Each is linked with MYBPHL in more than 1 cancer types. Because this analysis shows association rather than direction, both MYBPHL-to-partner and partner-to-MYBPHL results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MYBPHL→partner) and Y-score (partner→MYBPHL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	GSG1L2 →	+0.020	+5.022	<.001	.002	3	1
SKIN	RGSL1 →	+0.015	+4.977	.002	.007	3	1
SKIN	SPAG11A →	+0.073	+6.022	<.001	.001	3	1
SKIN	TIFAB →	+0.006	+5.415	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Exploration

MYBPHL survival (RNA) · tumor vs normal (RNA) · all MYBPHL data types