MYBPH

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, MYBPH RNA expression is significantly associated with the go_rna of many other GO terms, with 1,489 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MYBPH-associated GO terms across cancer lineages are Regulation of neurotrophin production, Negative regulation of glutamate secretion, and Positive regulation of mRNA metabolic process. Each is linked with MYBPH in more than 6 cancer types. Because this analysis shows association rather than direction, both MYBPH-to-partner and partner-to-MYBPH results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of neurotrophin production grouped by MYBPH-low versus MYBPH-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MYBPH→partner) and Y-score (partner→MYBPH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUNG_NSCLC_LUADRegulation of neurotrophin production →+0.923+0.900<.001.00137
LUNG_NSCLC_LUADNegative regulation of glutamate secretion →+1.514+0.997<.001<.00135
SOFT_TISSUEPositive regulation of mRNA metabolic process →+0.054+1.715<.001.00335
SOFT_TISSUENegative regulation of mRNA metabolic process →+0.053+1.246<.001.00634
SOFT_TISSUERegulation of DNA-templated transcription initiation →+0.040+1.563.009.00934
BLOOD_LeukemiaResponse to interleukin-4 →-0.165-1.516<.001<.00134
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,489 associations by consensus.

Regulation of neurotrophin production by MYBPH expression — LUNG_NSCLC_LUAD

Box plot of Regulation of neurotrophin production in MYBPH-low vs MYBPH-high samples in LUNG_NSCLC_LUAD.

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Exploration