Across TCGA patient cohorts, MYBPC1 mutation is significantly associated with the RNA expression of many other genes, with 5,638 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MYBPC1-associated genes across cancer lineages are CDC45, PES1, and CRYBB2P1. Each is linked with MYBPC1 in more than 3 cancer types. Because this analysis shows association rather than direction, both MYBPC1-to-partner and partner-to-MYBPC1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MYBPC1→partner) and Y-score (partner→MYBPC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CDC45 →	+0.899	+2.790	<.001	<.001	3	4
UCEC	PES1 →	+0.458	+1.847	<.001	<.001	3	4
UCEC	CRYBB2P1 →	+0.581	+2.758	<.001	<.001	3	4
UCEC	HSD17B1 →	+0.196	+2.021	.007	.005	3	4
UCEC	PDHX →	+0.454	+1.566	<.001	<.001	3	4
UCEC	ABHD5 →	+0.542	+1.523	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,638 associations by consensus.

Exploration

MYBPC1 survival (RNA) · tumor vs normal (RNA) · all MYBPC1 data types