Across TCGA patient cohorts, MYBPC1 mutation is significantly associated with the total protein of many other genes, with 60 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MYBPC1-associated genes across cancer lineages are ASNS, PCNA, and PKC-delta_pS664. Each is linked with MYBPC1 in more than 3 cancer types. Because this analysis shows association rather than direction, both MYBPC1-to-partner and partner-to-MYBPC1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MYBPC1→partner) and Y-score (partner→MYBPC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	ASNS →	+0.678	+2.467	<.001	.011	3	4
UCEC	PCNA →	+0.269	+2.415	<.001	<.001	3	3
UCEC	PKC-delta_pS664 →	-0.076	-1.115	.029	.026	3	3
UCEC	14-3-3_beta →	-0.063	-1.651	.031	.019	3	2
UCEC	EGFR_pY1068 →	-0.301	-1.906	<.001	<.001	3	2
UCEC	ERK2 →	+0.135	+1.115	.015	.026	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 60 associations by consensus.

Exploration

MYBPC1 survival (RNA) · tumor vs normal (RNA) · all MYBPC1 data types