Across TCGA cell cohorts, MYBPC1 mutation is significantly associated with the RNA expression of many other genes, with 63 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible MYBPC1-associated genes across cancer lineages are UGT2B10, DBX2, and AWAT2. Each is linked with MYBPC1 in more than 1 cancer types. Because this analysis shows association rather than direction, both MYBPC1-to-partner and partner-to-MYBPC1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MYBPC1→partner) and Y-score (partner→MYBPC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	UGT2B10 →	+0.402	+5.000	<.001	.006	3	1
PANCREAS	DBX2 →	+0.006	+5.000	<.001	.006	3	1
BLOOD_Leukemia	AWAT2 →	+0.012	+3.705	<.001	.007	3	1
BLOOD_Leukemia	GDNF →	+0.042	+4.000	<.001	.004	3	1
BLOOD_Leukemia	OR1N2 →	+0.028	+3.705	<.001	.007	3	1
BLOOD_Leukemia	PROP1 →	+0.018	+3.874	.009	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 63 associations by consensus.

Exploration

MYBPC1 survival (RNA) · tumor vs normal (RNA) · all MYBPC1 data types