MYBL2

Across TCGA cell cohorts, MYBL2 mutation is significantly associated with the RNA expression of many other genes, with 15 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible MYBL2-associated genes across cancer lineages are SERPINA7, C1orf158, and C1QC. Each is linked with MYBL2 in more than 1 cancer types. Because this analysis shows association rather than direction, both MYBL2-to-partner and partner-to-MYBL2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SERPINA7 grouped by MYBL2-low versus MYBL2-high in BLOOD_Myeloma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MYBL2→partner) and Y-score (partner→MYBL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	SERPINA7 →	+0.459	+4.807	<.001	.006	3	1
BLOOD_Myeloma	C1orf158 →	+0.053	+4.807	<.001	.006	3	1
BLOOD_Myeloma	C1QC →	+0.246	+4.807	<.001	.006	3	1
LUNG_SCLC	OR4B1 →	+0.055	+5.029	<.001	.006	3	1
BLOOD_Lymphoma	CABP5 →	+0.009	+3.867	<.001	.002	3	1
BLOOD_Lymphoma	RIPPLY1 →	+0.040	+3.606	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

SERPINA7 by MYBL2 expression — BLOOD_Myeloma

Explore this box plot interactively →