Across TCGA patient cohorts, MYBL1 protein abundance is significantly associated with the RNA expression of many other genes, with 17 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible MYBL1-associated genes across cancer lineages are NUMB, PTGFRN, and HTR2B. Each is linked with MYBL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both MYBL1-to-partner and partner-to-MYBL1 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MYBL1→partner) and Y-score (partner→MYBL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	NUMB →	-0.963	-0.726	.004	.005	2	1
BRCA	PTGFRN →	-1.406	-0.726	.002	.005	2	1
BRCA	HTR2B →	-0.563	-0.683	.005	.006	2	1
BRCA	ITM2B →	-0.450	-0.683	.002	.006	2	1
BRCA	MYC →	+1.833	+0.720	.006	.005	2	1
BRCA	PRDM5 →	-0.886	-0.719	<.001	.005	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 17 associations by consensus.

Exploration

MYBL1 survival (RNA) · tumor vs normal (RNA) · all MYBL1 data types