MYBL1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, MYBL1 mutation is significantly associated with the RNA expression of many other genes, with 4,044 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MYBL1-associated genes across cancer lineages are TBRG1, RRM2P2, and BLOC1S2P1. Each is linked with MYBL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both MYBL1-to-partner and partner-to-MYBL1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MYBL1→partner) and Y-score (partner→MYBL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECTBRG1 →+0.392+4.354<.001<.00132
COADRRM2P2 →+0.314+3.447.005.00932
COADBLOC1S2P1 →+0.182+3.665<.001.00432
COADRNU6-693P →+0.256+4.399<.001.00632
COADEIF4EBP1P1 →+0.352+3.701.009.00732
UCECTAF1C →+0.424+2.153<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,044 associations by consensus.

Exploration