Across TCGA cell cohorts, MYBL1 mutation is significantly associated with the RNA expression of many other genes, with 21 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible MYBL1-associated genes across cancer lineages are SPINK9, CYP11B1, and OR1L3. Each is linked with MYBL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both MYBL1-to-partner and partner-to-MYBL1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MYBL1→partner) and Y-score (partner→MYBL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	SPINK9 →	+0.264	+3.115	<.001	.004	3	2
LUNG_NSCLC_LUAD	CYP11B1 →	+0.011	+3.362	<.001	.007	3	1
SKIN	OR1L3 →	+0.022	+4.415	<.001	.007	3	1
SKIN	NPAP1 →	+0.004	+4.415	<.001	.007	3	1
SKIN	GYPB →	+0.136	+4.467	<.001	.004	3	1
CNS	SLC17A1 →	+0.072	+5.321	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 21 associations by consensus.

Exploration

MYBL1 survival (RNA) · tumor vs normal (RNA) · all MYBL1 data types