Across TCGA cell cohorts, MYBL1 mutation is significantly associated with the mutation status of many other genes, with 4,209 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible MYBL1-associated genes across cancer lineages are EVI5, DNMT3B, and NDST4. Each is linked with MYBL1 in more than 3 cancer types. Because this analysis shows association rather than direction, both MYBL1-to-partner and partner-to-MYBL1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MYBL1→partner) and Y-score (partner→MYBL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	EVI5 →	+4.297	+4.857	.009	.009	1	4
BLOOD_Lymphoma	DNMT3B →	+4.429	+5.247	.005	.005	1	4
BLOOD_Lymphoma	NDST4 →	+4.014	+4.969	.008	.008	1	4
BLOOD_Lymphoma	GRIK3 →	+4.429	+5.247	.005	.005	1	4
LARGE_INTESTINE	ERCC6 →	+2.222	+2.925	.001	.001	1	4
BREAST	HIVEP2 →	+4.297	+4.857	.009	.009	1	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,209 associations by consensus.

Exploration

MYBL1 survival (RNA) · tumor vs normal (RNA) · all MYBL1 data types