MYADML

Across TCGA pan-cancer cohorts, MYADML RNA is linked to patient survival in 16 of 34 cancer types, making it the most broadly survival-associated MYADML data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher MYADML RNA is associated with worse overall survival. In most high-consensus cancer types, elevated MYADML expression acts as an unfavorable survival marker, although some lineages such as UCEC and LAML show a favorable association.

KIRC, KICH, and ACC are the cancer types where MYADML RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Quartile	All	0.533	0.696	<.001	77	view →
KICH	DFS	Tertile	All	0.474	0.941	<.001	69	view →
ACC	DFS	Tertile	All	0.129	0.598	.002	45	view →
UCS	DFS	Tertile	IV	0.230	0.767	.009	36	view →
THCA	DFS	Tertile	III,IV	0.809	0.926	.003	34	view →
SKCM	OS	Tertile	III,IV	0.215	0.502	.002	33	view →
UCEC	DFS	Median	All	0.732	0.518	.004	24	view →
LGG	DFS	Tertile	All	0.269	0.433	.016	10	view →
UVM	DFS	Tertile	III,IV	0.032	0.727	<.001	9	view →
BRCA	DFS	Tertile	II,III,IV	0.481	0.522	.046	6	view →
LAML	DFS	Quartile	All	0.581	0.297	.040	4	view →
ESCA	DFS	Quartile	III,IV	0.458	0.256	.046	3	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 16 lineages.

MYADML–KIRC (OS)

Open the KIRC breakdown →