MYADM

Across TCGA patient cohorts, MYADM mutation is significantly associated with the total protein of many other genes, with 76 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MYADM-associated genes across cancer lineages are ATM, Cyclin-E1, and GAPDH. Each is linked with MYADM in more than 2 cancer types. Because this analysis shows association rather than direction, both MYADM-to-partner and partner-to-MYADM results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ATM grouped by MYADM-low versus MYADM-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MYADM→partner) and Y-score (partner→MYADM) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	ATM →	-0.786	-3.000	<.001	.035	3	3
COAD	Cyclin-E1 →	+0.316	+3.178	.010	.010	3	3
UCEC	GAPDH →	+0.540	+3.169	.001	<.001	3	3
UCEC	HER3 →	+0.194	+1.013	.023	.047	3	3
UCEC	MEK1 →	+0.356	+2.700	.001	.005	3	3
COAD	Axl →	-0.494	-3.151	<.001	.019	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 76 associations by consensus.

ATM by MYADM expression — COAD

Explore this box plot interactively →