MYADM

Across TCGA cell cohorts, MYADM mutation is significantly associated with the RNA expression of many other genes, with 12 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible MYADM-associated genes across cancer lineages are TGM7, CLLU1-AS1, and OR2S2. Each is linked with MYADM in more than 1 cancer types. Because this analysis shows association rather than direction, both MYADM-to-partner and partner-to-MYADM results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TGM7 grouped by MYADM-low versus MYADM-high in URINARY_TRACT.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MYADM→partner) and Y-score (partner→MYADM) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	TGM7 →	+0.013	+5.087	<.001	.004	3	1
URINARY_TRACT	CLLU1-AS1 →	+0.113	+5.087	<.001	.004	3	1
URINARY_TRACT	OR2S2 →	+0.036	+5.087	<.001	.004	3	1
URINARY_TRACT	CFAP97D2 →	+0.043	+5.087	<.001	.004	3	1
BLOOD_Leukemia	CCDC172 →	+0.046	+5.201	.005	.006	3	1
BLOOD_Leukemia	LCE2A →	+0.071	+5.969	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

TGM7 by MYADM expression — URINARY_TRACT

Explore this box plot interactively →