MXRA7

Across TCGA pan-cancer cohorts, MXRA7 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated MXRA7 data layer compared with 25 for mass-spec protein and 1 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher MXRA7 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated MXRA7 expression acts as an unfavorable survival marker, although some lineages such as HNSC show a favorable association.

PDAC, GBM, and CCRCC are the cancer types where MXRA7 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	OS	Quartile	All	0.288	0.484	.015	24	view →
GBM	OS	Quartile	All	0.678	0.903	.013	7	view →
CCRCC	DFS	Median	All	0.545	0.919	.005	6	view →
LSCC	DFS	Median	All	0.448	0.873	.016	5	view →
UCEC	OS	Median	II,III,IV	0.659	1.000	.021	4	view →
HNSC	DFS	Tertile	II,III,IV	0.884	0.714	.033	1	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

MXRA7–PDAC (OS)

Open the PDAC breakdown →