MXRA7

Across TCGA patient cohorts, MXRA7 mutation is significantly associated with the RNA expression of many other genes, with 60 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MXRA7-associated genes across cancer lineages are MIR4695, C7orf66, and PPIAP17. Each is linked with MXRA7 in more than 1 cancer types. Because this analysis shows association rather than direction, both MXRA7-to-partner and partner-to-MXRA7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR4695 grouped by MXRA7-low versus MXRA7-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MXRA7→partner) and Y-score (partner→MXRA7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	MIR4695 →	+0.437	+5.837	<.001	.001	3	2
UCEC	C7orf66 →	+0.483	+3.671	<.001	.003	3	2
UCEC	PPIAP17 →	+0.179	+4.163	.005	.001	3	2
BLCA	FGF7P1 →	+0.189	+7.640	<.001	.009	3	1
SKCM	RN7SL591P →	+0.145	+5.097	.005	.008	3	1
UCEC	OR10A3 →	+0.176	+3.599	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 60 associations by consensus.

MIR4695 by MXRA7 expression — CESC

Explore this box plot interactively →