MXI1

Across TCGA patient cohorts, MXI1 mutation is significantly associated with the RNA expression of many other genes, with 2,041 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MXI1-associated genes across cancer lineages are MTND4P1, RNU6-747P, and RNY4P3. Each is linked with MXI1 in more than 1 cancer types. Because this analysis shows association rather than direction, both MXI1-to-partner and partner-to-MXI1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MTND4P1 grouped by MXI1-low versus MXI1-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MXI1→partner) and Y-score (partner→MXI1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	MTND4P1 →	+0.143	+4.790	<.001	.006	3	2
LUAD	RNU6-747P →	+0.383	+7.930	<.001	.008	3	2
UCEC	RNY4P3 →	+0.258	+2.418	.004	.002	3	2
SKCM	MIR629 →	+0.424	+5.513	<.001	.004	3	2
UCEC	RPS10-NUDT3 →	+0.311	+2.461	<.001	.005	3	1
UCEC	LINC01607 →	-0.901	-3.679	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,041 associations by consensus.

MTND4P1 by MXI1 expression — COAD

Explore this box plot interactively →