Across TCGA patient cohorts, MXD3 RNA expression is significantly associated with the RNA expression of many other genes, with 18,337 significant associations in total. ACC shows the largest number of these associations.

The most reproducible MXD3-associated genes across cancer lineages are SPC24, PTTG1, and KIFC1. Each is linked with MXD3 in more than 33 cancer types. Because this analysis shows association rather than direction, both MXD3-to-partner and partner-to-MXD3 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MXD3→partner) and Y-score (partner→MXD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
THYM	SPC24 →	+2.557	+2.348	<.001	<.001	3	34
ACC	PTTG1 →	+2.643	+1.716	<.001	<.001	3	33
THYM	KIFC1 →	+2.328	+2.180	<.001	<.001	3	32
ACC	ASF1B →	+2.234	+1.682	<.001	<.001	3	32
THYM	SAC3D1 →	+1.781	+2.254	<.001	<.001	3	32
THYM	H2AX →	+2.161	+2.332	<.001	<.001	3	32

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,337 associations by consensus.

Exploration

MXD3 survival (RNA) · tumor vs normal (RNA) · all MXD3 data types