Across TCGA patient cohorts, MXD3 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,672 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MXD3-associated proteins across cancer lineages are DHFR, RRM2, and SMC2. Each is linked with MXD3 in more than 6 cancer types. Because this analysis shows association rather than direction, both MXD3-to-partner and partner-to-MXD3 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MXD3→partner) and Y-score (partner→MXD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	DHFR →	+0.653	+0.624	<.001	<.001	3	7
GBM	RRM2 →	+0.655	+0.678	<.001	<.001	3	7
GBM	SMC2 →	+0.732	+0.759	<.001	<.001	3	7
GBM	MCM4 →	+0.674	+0.731	<.001	<.001	3	7
OV	POLD3 →	+0.490	+0.833	.001	.002	3	6
LSCC	RBBP5_S497 →	+0.879	+0.406	<.001	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,672 associations by consensus.

Exploration

MXD3 survival (RNA) · tumor vs normal (RNA) · all MXD3 data types