Across TCGA patient cohorts, MXD3 protein abundance is significantly associated with the go_rna of many other GO terms, with 6 significant associations in total. OV shows the largest number of these associations.

The most reproducible MXD3-associated GO terms across cancer lineages are Monocarboxylic acid transport, Positive regulation of T-helper 1 type immune response, and Sequestering of triglyceride. Each is linked with MXD3 in more than 1 cancer types. Because this analysis shows association rather than direction, both MXD3-to-partner and partner-to-MXD3 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MXD3→partner) and Y-score (partner→MXD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	Monocarboxylic acid transport →	+0.032	+0.492	<.001	.009	3	1
OV	Positive regulation of T-helper 1 type immune response →	+0.117	+0.492	<.001	.009	1	1
OV	Sequestering of triglyceride →	+0.085	+0.492	.008	.009	1	1
OV	Protein deglutamylation →	+0.107	+0.492	.001	.009	1	1
OV	Protein side chain deglutamylation →	+0.170	+0.492	<.001	.009	1	1
OV	Neuropeptide signaling pathway →	+0.072	+0.492	.003	.009	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

Exploration

MXD3 survival (RNA) · tumor vs normal (RNA) · all MXD3 data types