Across TCGA cell cohorts, MXD3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,269 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MXD3-associated GO terms across cancer lineages are Microtubule organizing center organization, Centrosome cycle, and Negative regulation of metaphase/anaphase transition of cell cycle. Each is linked with MXD3 in more than 14 cancer types. Because this analysis shows association rather than direction, both MXD3-to-partner and partner-to-MXD3 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MXD3→partner) and Y-score (partner→MXD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Microtubule organizing center organization →	+0.102	+1.918	.002	.002	3	15
LUNG_NSCLC_LUSC	Centrosome cycle →	+0.108	+1.898	.002	.003	3	14
LUNG_NSCLC_LUSC	Negative regulation of metaphase/anaphase transition of cell cycle →	+0.154	+1.453	.001	.003	3	14
LUNG_NSCLC_LUSC	Negative regulation of chromosome separation →	+0.154	+1.453	.001	.003	3	14
BONE	DNA biosynthetic process →	+0.062	+1.277	.005	.001	3	14
LUNG_NSCLC_LUSC	Negative regulation of mitotic metaphase/anaphase transition →	+0.161	+1.423	.002	.004	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,269 associations by consensus.

Exploration

MXD3 survival (RNA) · tumor vs normal (RNA) · all MXD3 data types