Across TCGA pan-cancer cohorts, MXD1 mass-spec protein is linked to patient survival in 1 of 34 cancer types, making it a survival-associated MXD1 data layer compared with 23 for mass-spec protein and 4 for mutation status.
The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher MXD1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated MXD1 expression acts as an unfavorable survival marker.
PDAC are the cancer types where MXD1 mass-spec protein most reproducibly stratifies survival.