Across TCGA patient cohorts, MX2 protein abundance is significantly associated with the RNA expression of many other genes, with 10,621 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MX2-associated genes across cancer lineages are OAS3, OAS2, and IFIH1. Each is linked with MX2 in more than 9 cancer types. Because this analysis shows association rather than direction, both MX2-to-partner and partner-to-MX2 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MX2→partner) and Y-score (partner→MX2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	OAS3 →	+1.363	+0.773	<.001	<.001	3	10
LSCC	OAS2 →	+1.665	+0.901	<.001	<.001	3	10
HNSC	IFIH1 →	+1.413	+1.026	<.001	<.001	3	10
HNSC	STAT1 →	+1.023	+0.782	<.001	<.001	3	10
HNSC	CD80 →	+0.843	+0.682	<.001	<.001	3	10
HNSC	IFI6 →	+2.116	+1.111	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,621 associations by consensus.

Exploration

MX2 survival (RNA) · tumor vs normal (RNA) · all MX2 data types