Across TCGA patient cohorts, MX2 mutation is significantly associated with the RNA expression of many other genes, with 5,341 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MX2-associated genes across cancer lineages are LSM3, RP9P, and MRPL37. Each is linked with MX2 in more than 3 cancer types. Because this analysis shows association rather than direction, both MX2-to-partner and partner-to-MX2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MX2→partner) and Y-score (partner→MX2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	LSM3 →	+0.612	+3.000	<.001	<.001	3	4
SKCM	RP9P →	+0.583	+3.195	.003	.009	3	3
UCEC	MRPL37 →	+0.526	+2.632	<.001	<.001	3	3
UCEC	PPP1R8 →	+0.438	+1.807	<.001	<.001	3	3
UCEC	ZWINT →	+0.759	+1.807	<.001	<.001	3	3
UCEC	PEDS1-UBE2V1 →	+0.019	+1.458	<.001	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,341 associations by consensus.

Exploration

MX2 survival (RNA) · tumor vs normal (RNA) · all MX2 data types