MVP

Across TCGA patient cohorts, MVP protein abundance is significantly associated with the RNA expression of many other genes, with 21,515 significant associations in total. GBM shows the largest number of these associations.

The most reproducible MVP-associated genes across cancer lineages are CCNB1IP1, MEX3A, and STMN1. Each is linked with MVP in more than 6 cancer types. Because this analysis shows association rather than direction, both MVP-to-partner and partner-to-MVP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MVP versus CCNB1IP1 in UCEC, with a Pearson correlation of -0.31.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MVP→partner) and Y-score (partner→MVP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CCNB1IP1 →	-0.710	-0.329	<.001	<.001	3	7
GBM	MEX3A →	-1.519	-0.791	<.001	<.001	3	7
HNSC	STMN1 →	-0.947	-0.455	<.001	<.001	3	7
HNSC	ZNF286A →	-0.555	-0.444	.002	<.001	3	7
GBM	ZNF286B →	-0.726	-0.654	<.001	<.001	3	7
BRCA	ABLIM3 →	+1.503	+0.452	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 21,515 associations by consensus.

MVP vs CCNB1IP1 — UCEC

Explore this scatter interactively →