MVP

Across TCGA cell cohorts, MVP protein abundance is significantly associated with the go_rna of many other GO terms, with 4,326 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible MVP-associated GO terms across cancer lineages are Recognition of apoptotic cell, Positive regulation of nitric oxide mediated signal transduction, and Phagocytosis, recognition. Each is linked with MVP in more than 11 cancer types. Because this analysis shows association rather than direction, both MVP-to-partner and partner-to-MVP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Recognition of apoptotic cell grouped by MVP-low versus MVP-high in PANCREAS.

protein abundance associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MVP→partner) and Y-score (partner→MVP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Recognition of apoptotic cell →	+0.291	+1.953	.002	.006	3	12
SOFT_TISSUE	Positive regulation of nitric oxide mediated signal transduction →	+0.338	+2.550	.003	.004	3	10
OVARY	Phagocytosis, recognition →	+0.432	+1.274	.009	<.001	3	7
LUNG_SCLC	Chromosome condensation →	-0.144	-0.707	<.001	.009	3	5
PANCREAS	Cellular response to acidic pH →	+0.184	+1.447	.001	<.001	3	5
CNS	NAD+ metabolic process →	+0.099	+1.128	.004	.005	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,326 associations by consensus.

Recognition of apoptotic cell by MVP expression — PANCREAS

Explore this box plot interactively →