MVB12A

Across TCGA patient cohorts, MVB12A protein abundance is significantly associated with the RNA expression of many other genes, with 13,643 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MVB12A-associated genes across cancer lineages are SIGLEC1, ZNF699, and ZNF558. Each is linked with MVB12A in more than 4 cancer types. Because this analysis shows association rather than direction, both MVB12A-to-partner and partner-to-MVB12A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MVB12A versus SIGLEC1 in LSCC, with a Pearson correlation of -0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MVB12A→partner) and Y-score (partner→MVB12A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SIGLEC1 →	-0.839	-0.211	<.001	<.001	3	5
UCEC	ZNF699 →	+0.515	+0.298	<.001	<.001	3	5
OV	ZNF558 →	+0.601	+0.289	<.001	<.001	3	5
HNSC	AKNA →	-0.917	-0.232	<.001	.001	3	4
LSCC	DOCK8 →	-0.783	-0.262	<.001	<.001	3	4
LSCC	HRH2 →	-0.836	-0.289	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,643 associations by consensus.

MVB12A vs SIGLEC1 — LSCC

Explore this scatter interactively →