MVB12A

Across TCGA cell cohorts, MVB12A RNA expression is significantly associated with the go_rna of many other GO terms, with 2,548 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible MVB12A-associated GO terms across cancer lineages are Energy coupled proton transmembrane transport, against electrochemical gradient, Electron transport coupled proton transport, and Pentose-phosphate shunt, oxidative branch. Each is linked with MVB12A in more than 11 cancer types. Because this analysis shows association rather than direction, both MVB12A-to-partner and partner-to-MVB12A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Energy coupled proton transmembrane transport, against electrochemical gradient grouped by MVB12A-low versus MVB12A-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MVB12A→partner) and Y-score (partner→MVB12A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Energy coupled proton transmembrane transport, against electrochemical gradient →	+0.085	+0.879	<.001	<.001	3	12
OVARY	Electron transport coupled proton transport →	+0.085	+0.879	<.001	<.001	3	12
CNS	Pentose-phosphate shunt, oxidative branch →	+0.121	+0.758	<.001	<.001	3	12
CNS	Negative regulation of protein localization to chromatin →	+0.110	+0.606	<.001	.001	3	10
SKIN	Positive regulation of anaphase-promoting complex-dependent catabolic process →	+0.092	+0.726	<.001	.003	3	9
UPPER_AERODIGESTIVE_TRACT	Positive regulation of intracellular estrogen receptor signaling pathway →	+0.115	+0.784	.005	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,548 associations by consensus.

Energy coupled proton transmembrane transport, against electrochemical gradient by MVB12A expression — OVARY

Explore this box plot interactively →