MUS81

Across TCGA cell cohorts, MUS81 RNA expression is significantly associated with the RNA expression of many other genes, with 9,062 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MUS81-associated genes across cancer lineages are RELA, MAP3K11, and PCNX3. Each is linked with MUS81 in more than 19 cancer types. Because this analysis shows association rather than direction, both MUS81-to-partner and partner-to-MUS81 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MUS81 versus RELA in LIVER, with a Pearson correlation of 0.64.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MUS81→partner) and Y-score (partner→MUS81) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	RELA →	+1.077	+1.148	.002	.003	2	20
BONE	MAP3K11 →	+1.195	+0.860	<.001	.001	3	18
UPPER_AERODIGESTIVE_TRACT	PCNX3 →	+1.051	+0.958	<.001	<.001	3	17
BLOOD_Myeloma	KAT5 →	+0.872	+0.638	<.001	.007	2	17
URINARY_TRACT	ZBTB17 →	+0.974	+1.102	<.001	<.001	3	16
SKIN	NXF1 →	+0.717	+1.032	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,062 associations by consensus.

MUS81 vs RELA — LIVER

Explore this scatter interactively →