MUL1

Across TCGA pan-cancer cohorts, MUL1 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated MUL1 data layer compared with 23 for mass-spec protein and 1 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher MUL1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated MUL1 expression acts as an unfavorable survival marker, although some lineages such as COAD and CCRCC show a favorable association.

PDAC, COAD, and CCRCC are the cancer types where MUL1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	DFS	Tertile	All	0.216	0.618	<.001	22	view →
COAD	DFS	Median	II,III,IV	1.000	0.915	.023	18	view →
CCRCC	OS	Median	III,IV	0.989	0.133	.020	7	view →
UCEC	DFS	Quartile	All	0.799	1.000	.014	6	view →
HNSC	DFS	Median	IV	0.915	1.000	.036	1	view →
GBM	OS	Median	All	0.876	0.755	.048	1	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

MUL1–PDAC (DFS)

Open the PDAC breakdown →