MUCL1

Across TCGA patient cohorts, MUCL1 protein abundance is significantly associated with the RNA expression of many other genes, with 2,010 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible MUCL1-associated genes across cancer lineages are SUV39H1, CRISPLD2, and FOXM1. Each is linked with MUCL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both MUCL1-to-partner and partner-to-MUCL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MUCL1 versus SUV39H1 in LSCC, with a Pearson correlation of -0.85.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MUCL1→partner) and Y-score (partner→MUCL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SUV39H1 →	-0.958	-3.090	.003	.004	3	2
BRCA	CRISPLD2 →	+0.906	+1.616	<.001	<.001	3	2
BRCA	FOXM1 →	-1.260	-2.217	<.001	<.001	3	2
HNSC	SPARC →	+0.908	+1.819	.005	<.001	3	2
HNSC	CLCN2 →	-0.488	-1.135	.003	<.001	3	2
LSCC	CALD1 →	+1.056	+2.356	.008	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,010 associations by consensus.

MUCL1 vs SUV39H1 — LSCC

Explore this scatter interactively →