MUCL1

Across TCGA patient cohorts, MUCL1 mutation is significantly associated with the immune_cell of many other genes, with 4 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible MUCL1-associated genes across cancer lineages are CLP, Macrophages M1, and Adipocytes. Each is linked with MUCL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both MUCL1-to-partner and partner-to-MUCL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CLP grouped by MUCL1-low versus MUCL1-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MUCL1→partner) and Y-score (partner→MUCL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	CLP →	+0.078	+1.893	.030	.031	3	1
SKCM	Macrophages M1 →	-0.025	-2.527	.033	.011	3	1
UCEC	Adipocytes →	+0.022	+2.507	.040	.022	3	1
UCEC	Neutrophils →	+0.022	+2.166	<.001	.040	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

CLP by MUCL1 expression — SKCM

Explore this box plot interactively →