Across TCGA patient cohorts, MUC6 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,816 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible MUC6-associated proteins across cancer lineages are RAB27B, PHKA1_S758, and POGZ_S1364. Each is linked with MUC6 in more than 3 cancer types. Because this analysis shows association rather than direction, both MUC6-to-partner and partner-to-MUC6 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MUC6→partner) and Y-score (partner→MUC6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RAB27B →	+0.965	+1.713	<.001	<.001	3	4
GBM	PHKA1_S758 →	-0.616	-0.284	<.001	<.001	3	3
OV	POGZ_S1364 →	+0.582	+0.840	<.001	.005	3	3
CCRCC	PPM1B_S386 →	+0.823	+0.160	<.001	<.001	3	3
PDAC	SEC16A_S2295 →	-0.687	-1.516	<.001	<.001	3	3
COAD	HSPH1 →	-0.570	-1.128	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,816 associations by consensus.

Exploration

MUC6 survival (RNA) · tumor vs normal (RNA) · all MUC6 data types