MUC4

Across TCGA patient cohorts, MUC4 protein abundance is significantly associated with the RNA expression of many other genes, with 7,331 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible MUC4-associated genes across cancer lineages are STS, CEACAM5, and MUC5B. Each is linked with MUC4 in more than 3 cancer types. Because this analysis shows association rather than direction, both MUC4-to-partner and partner-to-MUC4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MUC4 versus STS in COAD, with a Pearson correlation of 0.47.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MUC4→partner) and Y-score (partner→MUC4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	STS →	+0.841	+1.051	<.001	<.001	3	4
UCEC	CEACAM5 →	+2.953	+1.169	<.001	<.001	3	4
UCEC	MUC5B →	+3.131	+0.819	<.001	.002	3	4
HNSC	BPIFB1 →	+2.562	+0.551	<.001	<.001	3	4
HNSC	LCN2 →	+2.053	+0.679	<.001	<.001	3	4
HNSC	LIPH →	+1.058	+0.634	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,331 associations by consensus.

MUC4 vs STS — COAD

Explore this scatter interactively →