MUC22

Across TCGA patient cohorts, MUC22 RNA expression is significantly associated with the RNA expression of many other genes, with 6,557 significant associations in total. KIRP shows the largest number of these associations.

The most reproducible MUC22-associated genes across cancer lineages are MUC21, HCG22, and SCEL. Each is linked with MUC22 in more than 16 cancer types. Because this analysis shows association rather than direction, both MUC22-to-partner and partner-to-MUC22 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MUC22 versus MUC21 in ESCA, with a Pearson correlation of 0.76.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MUC22→partner) and Y-score (partner→MUC22) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	MUC21 →	+3.685	+1.167	<.001	<.001	3	17
ESCA	HCG22 →	+1.066	+1.115	<.001	<.001	3	14
ESCA	SCEL →	+2.783	+1.083	<.001	<.001	3	13
ESCA	RNF222 →	+1.129	+1.030	<.001	<.001	3	13
ESCA	S100A9 →	+3.463	+1.147	<.001	<.001	3	12
ESCA	IVL →	+2.918	+1.099	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,557 associations by consensus.

MUC22 vs MUC21 — ESCA

Explore this scatter interactively →