MUC17

Across TCGA patient cohorts, MUC17 protein abundance is significantly associated with the RNA expression of many other genes, with 100 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible MUC17-associated genes across cancer lineages are TRIM9, RBFA, and IKBKB. Each is linked with MUC17 in more than 1 cancer types. Because this analysis shows association rather than direction, both MUC17-to-partner and partner-to-MUC17 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, MUC17 versus TRIM9 in PDAC, with a Pearson correlation of -0.51.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MUC17→partner) and Y-score (partner→MUC17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	TRIM9 →	-0.353	-1.355	.005	.004	3	1
PDAC	RBFA →	-0.461	-1.630	.002	.004	3	1
PDAC	IKBKB →	-0.860	-2.236	.004	.002	3	1
PDAC	UST →	-0.883	-1.649	<.001	.002	3	1
PDAC	RELCH →	-0.468	-1.519	.006	.001	3	1
PDAC	C18orf25 →	-0.678	-1.908	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 100 associations by consensus.

MUC17 vs TRIM9 — PDAC

Explore this scatter interactively →