MUC17

Across TCGA cell cohorts, MUC17 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,475 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible MUC17-associated GO terms across cancer lineages are Actin filament capping, Regulation of clathrin coat assembly, and Vesicle transport along actin filament. Each is linked with MUC17 in more than 3 cancer types. Because this analysis shows association rather than direction, both MUC17-to-partner and partner-to-MUC17 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Actin filament capping grouped by MUC17-low versus MUC17-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MUC17→partner) and Y-score (partner→MUC17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Actin filament capping →	+0.159	+2.498	<.001	.002	3	4
STOMACH	Regulation of clathrin coat assembly →	+0.138	+1.772	.009	.007	3	4
STOMACH	Vesicle transport along actin filament →	+0.154	+2.167	<.001	<.001	3	3
BLOOD_Lymphoma	Negative regulation of translational initiation →	+0.078	+0.017	<.001	.008	3	3
CNS	Phosphatidylinositol biosynthetic process →	+0.038	+0.004	.001	.007	3	3
CNS	Error-free translesion synthesis →	+0.073	+0.004	.002	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,475 associations by consensus.

Actin filament capping by MUC17 expression — STOMACH

Explore this box plot interactively →