Across TCGA patient cohorts, MUC1 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,484 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MUC1-associated proteins across cancer lineages are MISP3_S91, RBM47, and TJP3. Each is linked with MUC1 in more than 4 cancer types. Because this analysis shows association rather than direction, both MUC1-to-partner and partner-to-MUC1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (MUC1→partner) and Y-score (partner→MUC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MISP3_S91 →	+0.778	+1.780	<.001	<.001	3	5
GBM	RBM47 →	+0.411	+0.468	.002	.003	3	5
BRCA	TJP3 →	+0.585	+1.653	<.001	<.001	3	5
BRCA	TJP3_S112 →	+0.910	+1.346	<.001	.002	3	5
HNSC	TJP3_S346 →	+0.852	+1.248	<.001	<.001	3	5
HNSC	PIGR →	+1.074	+1.092	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,484 associations by consensus.

Exploration

MUC1 survival (RNA) · tumor vs normal (RNA) · all MUC1 data types