Across TCGA patient cohorts, MUC1 protein abundance is significantly associated with the RNA expression of many other genes, with 18,081 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible MUC1-associated genes across cancer lineages are LRG1, STS, and FSD1. Each is linked with MUC1 in more than 7 cancer types. Because this analysis shows association rather than direction, both MUC1-to-partner and partner-to-MUC1 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MUC1→partner) and Y-score (partner→MUC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	LRG1 →	+1.628	+0.600	<.001	<.001	3	8
BRCA	STS →	+0.788	+0.670	<.001	<.001	3	6
BRCA	FSD1 →	-1.039	-0.721	<.001	<.001	3	6
GBM	TC2N →	+1.108	+0.519	.002	<.001	3	6
BRCA	TPX2 →	-1.256	-0.892	<.001	<.001	3	6
OV	ST6GALNAC1 →	+1.669	+0.816	.002	.003	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,081 associations by consensus.

Exploration

MUC1 survival (RNA) · tumor vs normal (RNA) · all MUC1 data types