Across TCGA patient cohorts, MUC1 mutation is significantly associated with the RNA expression of many other genes, with 586 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible MUC1-associated genes across cancer lineages are OR7E16P, MIR6779, and RNU6-1026P. Each is linked with MUC1 in more than 1 cancer types. Because this analysis shows association rather than direction, both MUC1-to-partner and partner-to-MUC1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (MUC1→partner) and Y-score (partner→MUC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	OR7E16P →	+0.026	+4.559	<.001	.006	3	2
CESC	MIR6779 →	+0.723	+4.824	<.001	<.001	3	2
UCEC	RNU6-1026P →	+0.230	+3.200	.006	.006	3	2
UCEC	RN7SL317P →	+0.143	+2.456	.002	.006	3	2
SKCM	MTCO1P5 →	+0.084	+4.680	<.001	.007	3	2
BRCA	RNU6-255P →	+0.376	+6.866	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 586 associations by consensus.

Exploration

MUC1 survival (RNA) · tumor vs normal (RNA) · all MUC1 data types