Across TCGA cell cohorts, MUC1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,204 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible MUC1-associated GO terms across cancer lineages are Negative regulation of NK T cell activation, UDP-galactose transmembrane transport, and Positive regulation of neuron apoptotic process. Each is linked with MUC1 in more than 10 cancer types. Because this analysis shows association rather than direction, both MUC1-to-partner and partner-to-MUC1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MUC1→partner) and Y-score (partner→MUC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Negative regulation of NK T cell activation →	+1.246	+1.875	<.001	<.001	3	10
PANCREAS	UDP-galactose transmembrane transport →	+0.124	+3.588	<.001	<.001	3	10
BONE	Positive regulation of neuron apoptotic process →	+0.085	+0.978	<.001	.004	3	10
BLOOD_Lymphoma	Negative regulation of peptidase activity →	+0.867	+2.919	<.001	<.001	3	10
BLOOD_Lymphoma	Macrophage colony-stimulating factor signaling pathway →	+0.719	+1.347	<.001	.001	3	10
BLOOD_Lymphoma	Fusion of virus membrane with host plasma membrane →	+1.039	+1.943	<.001	.005	2	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,204 associations by consensus.

Exploration

MUC1 survival (RNA) · tumor vs normal (RNA) · all MUC1 data types