MTX2

Across TCGA cell cohorts, MTX2 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,595 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MTX2-associated GO terms across cancer lineages are Mitochondrial outer membrane translocase complex assembly, Mitochondrial electron transport, NADH to ubiquinone, and Mitochondrial membrane organization. Each is linked with MTX2 in more than 10 cancer types. Because this analysis shows association rather than direction, both MTX2-to-partner and partner-to-MTX2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Mitochondrial outer membrane translocase complex assembly grouped by MTX2-low versus MTX2-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MTX2→partner) and Y-score (partner→MTX2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Mitochondrial outer membrane translocase complex assembly →	+0.096	+0.678	.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Mitochondrial electron transport, NADH to ubiquinone →	+0.088	+0.588	.005	.003	3	10
STOMACH	Mitochondrial membrane organization →	+0.061	+0.375	<.001	.005	3	9
UPPER_AERODIGESTIVE_TRACT	Medulla oblongata development →	+0.099	+0.401	.001	.006	3	9
LUNG_SCLC	Aerobic electron transport chain →	+0.088	+0.575	.009	.002	2	10
BONE	Protein insertion into mitochondrial membrane →	+0.092	+0.529	.004	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,595 associations by consensus.

Mitochondrial outer membrane translocase complex assembly by MTX2 expression — URINARY_TRACT

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