MTX1

Across TCGA cell cohorts, MTX1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,403 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible MTX1-associated GO terms across cancer lineages are Threonyl-tRNA aminoacylation, Glucoside transport, and mRNA 3'-end processing. Each is linked with MTX1 in more than 10 cancer types. Because this analysis shows association rather than direction, both MTX1-to-partner and partner-to-MTX1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Threonyl-tRNA aminoacylation grouped by MTX1-low versus MTX1-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MTX1→partner) and Y-score (partner→MTX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Threonyl-tRNA aminoacylation →	+0.110	+0.675	<.001	<.001	3	11
LIVER	Glucoside transport →	+0.256	+0.521	.009	.005	3	9
LARGE_INTESTINE	mRNA 3'-end processing →	+0.082	+0.681	<.001	<.001	3	9
PANCREAS	Porphyrin-containing compound metabolic process →	+0.097	+0.467	<.001	.001	3	9
LUNG_NSCLC_LUSC	Porphyrin-containing compound biosynthetic process →	+0.123	+0.631	.002	.001	3	9
STOMACH	Spliceosome conformational change to release U4 (or U4atac) and U1 (or U11) →	+0.121	+0.760	.003	.002	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,403 associations by consensus.

Threonyl-tRNA aminoacylation by MTX1 expression — BREAST

Explore this box plot interactively →