MTUS2

Across TCGA cell cohorts, MTUS2 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,221 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible MTUS2-associated GO terms across cancer lineages are Negative regulation of T-helper cell differentiation, Cellular respiration, and Negative regulation of myoblast fusion. Each is linked with MTUS2 in more than 6 cancer types. Because this analysis shows association rather than direction, both MTUS2-to-partner and partner-to-MTUS2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of T-helper cell differentiation grouped by MTUS2-low versus MTUS2-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (MTUS2→partner) and Y-score (partner→MTUS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Negative regulation of T-helper cell differentiation →	-0.090	-0.400	.001	.004	2	7
LUNG_NSCLC_LUSC	Cellular respiration →	+0.066	+0.183	.002	.007	3	6
BREAST	Negative regulation of myoblast fusion →	+0.076	+0.478	.002	.003	3	6
SKIN	Alternative mRNA splicing, via spliceosome →	+0.069	+0.164	.001	.007	2	7
BLOOD_Leukemia	Negative regulation of transcription by RNA polymerase I →	+0.096	+0.689	<.001	<.001	3	6
LUNG_NSCLC_LUSC	Energy derivation by oxidation of organic compounds →	+0.054	+0.185	.002	.006	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,221 associations by consensus.

Negative regulation of T-helper cell differentiation by MTUS2 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →