MTUS2-AS1

Across TCGA pan-cancer cohorts, MTUS2-AS1 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated MTUS2-AS1 data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher MTUS2-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated MTUS2-AS1 expression acts as an unfavorable survival marker, although some lineages such as MESO and LIHC show a favorable association.

ACC, KIRC, and UVM are the cancer types where MTUS2-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	OS	Quartile	II,III,IV	0.265	0.674	<.001	133	view →
KIRC	DFS	Median	All	0.510	0.702	<.001	120	view →
UVM	DFS	Median	All	0.393	0.779	<.001	111	view →
THYM	OS	Tertile	All	0.891	0.988	.008	47	view →
KIRP	DFS	Tertile	All	0.412	0.680	.007	37	view →
LUAD	OS	Quartile	III,IV	0.288	0.557	.004	35	view →
MESO	OS	Median	II,III,IV	0.735	0.311	.007	27	view →
BLCA	DFS	Median	III,IV	0.375	0.549	.008	23	view →
LIHC	OS	Tertile	All	0.886	0.714	.009	17	view →
GBM	DFS	Tertile	All	0.193	0.345	.011	17	view →
CESC	OS	Median	III,IV	0.236	0.645	.021	16	view →
COAD	DFS	Quartile	All	0.420	0.654	.008	11	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

MTUS2-AS1–ACC (OS)

Open the ACC breakdown →